Fri Jan 05 2024

33 articles - From Friday Dec 29 2023 to Friday Jan 05 2024

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis

The Epidemiology of Inflammatory Bowel Disease in Oceania: A Systematic Review and Meta-Analysis of Incidence and Prevalence.

The incidence and prevalence of IBD in Oceania is high. The studies were heterogeneous and there were several geographic areas with no information, highlighting the need for more epidemiological studies of IBD.

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J Crohns Colitis

DIAGNOSTIC ACCURACY OF INTESTINAL ULTRASOUND IN THE DETECTION OF INTRA-ABDOMINAL COMPLICATIONS IN CROHN'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS.

IUS is accurate for the diagnosis of intra-abdominal complications in CD. As a non-invasive, point-of-care modality, IUS is recommended as the first-line imaging tool if there is a suspicion of CD-related intra-abdominal complications.

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Pancreatology

Association of high-risk stigmata and worrisome features with advanced neoplasia in intraductal papillary mucinous neoplasms (IPMN): A systematic review.

This systematic review provides evidence supporting the improved diagnostic accuracy of ICG2017 in identifying high-risk lesions of IPMN. The multidisciplinary incorporation of HRS and WF based on imaging findings and clinical symptoms is crucial. These findings should inform the revision of ICG2017, enhancing the evaluation and management of IPMN patients. By implementing these recommendations, clinicians can make more informed decisions, leading to better diagnosis and treatment outcomes for high-risk IPMN cases.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase non-persistent genotype.

Increased levels of Bifidobacterium indicate an adaptation of the gut microbiota upon repetitive consumption of incremental doses of lactose, which was well-tolerated as demonstrated by reduced expired hydrogen levels during the second 25g lactose HBT. Bifidobacteria metabolize lactose without gas production thereby potentially reducing intestinal gas formation in the gut of individuals with the LNP-genotype. This increased lactose tolerance possibly lifts the necessity to remove nutrient-rich dairy foods completely from the diet. Registration number of clinical trial The trial is registered at the International Clinical Trials Registry Platform NL9516 The effect of dietary lactose in lactase non-persistent individuals on gut microbiota.

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Climate-based variability in the essential fatty acid composition of soybean oil.

From this work, it was determined that soybean oil manufactured from soybeans in the southern United States may contain insufficient ALA to meet human nutritional needs because of high-daytime temperatures. This work suggests that climate-based variation may result in many human populations not achieving an adequate daily intake of ALA.

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Estimation of 24-hour urinary sodium and potassium excretion among Chinese adults: a cross-sectional study from the China National Nutrition Survey.

The first nationwide survey with 24-h urine collection confirmed that mean sodium intake in Chinese adults was more than twice the upper limit, whereas mean potassium intake was <60% of the lower limit, recommended by the World Health Organization. Urgent measures should be taken to reduce sodium intake and increase potassium intake in China.

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Food Insecurity, Neighborhood Food Environment, and Health Disparities: State of the Science, Research Gaps and Opportunities.

The workshop had three research objectives: 1) summarize the state of the science and knowledge gaps related to food insecurity, neighborhood food environments, and nutrition health disparities, 2) identify research opportunities and strategies to address research gaps, and 3) examine evidence-based interventions and implementation approaches to address food insecurity and neighborhood food environments to promote health equity. This article summarizes workshop proceedings and describes research gaps and future opportunities that emerged from discussions.

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Hemoglobin measurement in venous blood versus single-drop and pooled capillary blood: A method-comparison study in a controlled and survey setting in Uganda among children and women.

Future research is also needed to evaluate the implications of using venous versus capillary blood in population-based surveys. 720-OAA-18C-00083;

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Low dose daily folic acid (400 µg) supplementation does not affect regulation of folate transporters found present throughout the terminal ileum and colon of humans: a randomized clinical trial.

Folate transporters are present throughout the terminal ileum and colon; there is little evidence that a low dose folic acid supplementation affects colonic absorption. Clinical trial registry number NCT03421483

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Plasma lipidomic markers of diet quality are associated with incident coronary heart disease in American Indian adults: the Strong Heart Family Study.

We identified lipidomic markers of diet quality in American Indian adults. Some diet-related lipids are associated with risk of CHD beyond established risk factors.

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Polymorphisms in the choline transporter SLC44A1 are associated with reduced cognitive performance in normotypic but not prenatal alcohol-exposed children.

These alleles were previously associated with greater cognitive improvement in children with PAE who received supplemental choline. The findings endorse that choline benefits cognitive development in normotypic children and those with PAE.

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Post Hoc Analysis of Food Costs Associated with Dietary Approaches to Stop Hypertension (DASH) Diet, Whole Food, Plant-Based Diet, and Typical Baseline Diet of Individuals with Insulin-Treated Type 2 Diabetes Mellitus in a Non-Randomized Crossover Trial with Meals Provided.

In this short-term study with meals provided, the food costs of plant-predominant diets offering substantial metabolic health benefits were less than or similar to baseline food costs of adults with insulin-treated T2DM. Longer-term data without meal provision are needed for more generalizable results. Clinicaltrials GOV ID NCT04048642 TRIAL REGISTRATION

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Inflamm Bowel Dis

Infliximab Monotherapy vs Combination Therapy for Pediatric Crohn's Disease Exhibit Similar Pharmacokinetics.

This study suggests that there are no PK differences (TLs and CL) between combo and mono therapy in pediatric CD patients who started IFX.

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The Clinical Interpretation of Noninferiority Trials.

We discuss a clinically oriented approach to interpretation of results with a focus on confidence intervals and recommend that readers base their judgments regarding noninferiority on margins reflecting patient values and preferences rather than those set by investigators. We provide examples from trials in inflammatory bowel diseases.

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Unique Metabolomic and Lipidomic Profile in Serum From Patients With Crohn's Disease and Ulcerative Colitis Compared With Healthy Control Individuals.

Metabolomic assessment of serum samples facilitated the differentiation of IBD patients and HC individuals. These differences were constituted by changes in amino acid and lipoprotein levels. Furthermore, disease activity in IBD patients was associated with decreased levels of the atheroprotective apolipoproteins A1 and A2.

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J Crohns Colitis

D-alanine inhibits murine intestinal inflammation by suppressing IL-12 and IL-23 production in macrophages.

Our results suggest that D-alanine prevents dextran sulfate sodium-induced colitis in mice and suppresses IL-12p35 and IL-23p19 production in macrophages.

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Liver Transpl

Caregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multi-center SOCIAL-Tx study.

We identified barriers to providing effective social care in pediatric LT, primarily a lack of comfort assessing and addressing new social risks in the post-transplant period. Addressing these barriers should enhance social care delivery and improve outcomes for these children.

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Quantitative methods for optimizing patient outcomes in liver transplantation.

In this review, we describe quantitative methods applied to organ transplantation, with a focus on LT. These include quantitative methods for 1) utilizing and allocating donor organs equitably and optimally, 2) improving surgical planning through preoperative imaging, 3) monitoring of graft and immune status, 4) determining immunosuppressant doses, and 5) establishing and maintaining the health of graft and patient post LT.

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Pancreas

Clinical Significance of Increased Skeletal Muscle Mass During Nab-Paclitaxel Plus Gemcitabine Treatment in Patients With Advanced Pancreatic Cancer.

Increased skeletal muscle mass during AG treatment might contribute to the higher prevalence of 2L chemotherapy induction in patients with APC.

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Pancreatology

Clinical usefulness of routinely performed drain fluid cultures after pancreaticoduodenectomy. A new ally to predict patients' outcomes?

Bacterial contamination of surgical drains predicts the development of B/C grade POPF and other major complications after PD. Therefore, we suggest the routine use of fluid drain cultures following PD.

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Duodenal and pancreatic tissue microbiome profiles of PPI users and non-users.

However, some differences in pancreas tissue beta diversity were observed between PPI users and non-users. In summary, we find differences in the microbiome profiles of the pancreas head versus the pancreatic body/tail and we find PPI use is associated with alterations in duodenal and pancreatic tissue microbiome profiles.

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Limited exposure to pancreatic ERCP during advanced endoscopy training impacts competence and performance in independent practice.

Advanced endoscopy training offers a low level of exposure to pancreatic ERCP, which is mirrored in independent practice, highlighting the inadequate training in pancreatic ERCP. Given the complexity of pancreatic ERCP, novel strategies are warranted to improve training in pancreatic ERCP.

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Remission of organ failure in patients with predicted severe acute pancreatitis treated by somatostation, octreotide and cyclooxygenase-2 inhibitors.

Somatostatin or its analogs and cyclooxygenase-2 inhibitors are promising for OF prevention and remission in patients with predicted SAP. The acceptance of combined strategies in the real world has increased, and the occurrence of SAP has decreased annually.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Bring balance to the (electrolyte) force - more actions needed to shift the dietary sodium-to-potassium ratio in China.

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Climate change, plant composition, and human nutrition.

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Should we remove wine from the Mediterranean diet?: a narrative review.

CLINICAL TRIAL REGISTRY NUMBER: PREDIMED, ISRCTN35739639, SUN, CLINICALTRIALS. GOV IDENTIFIER: NCT02669602,

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The critical need for novel precision medicine methodologies in fetal alcohol spectrum disorders.

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J Crohns Colitis

Refining the Concept of Microscopic Colitis: HLA Signatures Discriminating Collagenous and Lymphocytic Colitis.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Introducing the Fellows' Corner: Fostering Early Career Voices in Healthcare.

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Older Adults With Inflammatory Bowel Disease Are at Higher Risk of Developing Antibodies to Infliximab.

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Liver Transpl

Letter to the Editor: Does therapeutic plasma exchange (TPE) have a role in the treatment of hepatocellular carcinoma?"

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Reply: Does therapeutic plasma exchange really have a role in the treatment of hepatocellular carcinoma?

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Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr

The Centers for Disease Control and Prevention does not recommend race-adjusted thresholds to define anemia.

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